主持研究项目：

1.食品加工高新技术装备及关键器件的研发与应用，科技部国家重点研发计划项目课题（2024YFD2101101），2024-2027，主持，680万

2.特色果蔬数字化运输及精准保鲜关键技术的研发与应用，江苏省重点研发计划现代农业（BE2023310），2023-2025，主持，80万

3.基于新型微波感知系统的食品质量与安全在线评估及检测方法研究，国家自然科学基金国际(地区)合作与交流项目课题（32261133623），2023-2025，主持，50万

4.食品安全快速检测与质量保障技术的研究，科技部高端外国专家项目（DL2022144002L），2022-2023，主持，30万

5.食品添加过程产生保守性标志物的多谱联用技术研发，国家“十三五”重点研发计划子课题(2018YFC1602303)，2018–2021，主持，74万

6.植物源新型绿色防腐保鲜剂研发，“十二五”国家科技支撑计划子课题（2015BAD16B01），2015-2017，主持，30万

7.多领域中重金属检测方法的应用研究，科技部重大仪器设备开发专项课题（2012YQ170003），2012-2015，主持，95万

8.磁性分子印迹聚合物SERS基底的构筑及对抗生素残留的检测，国家自然科学基金青年科学基金（21203076），2013-2015，主持，25万

9.硝基呋喃类抗菌药非标记、特异性识别技术研发与应用研究，江苏省自然科学基金面上项目（BK20171139），2017-2019，主持，10万

代表性论文

[1]Cheng, J., Shen, Y., Gu, Y.L., Xiang, T.Y., Shen, H., Wang, Y., Hu, Z.Y., Zheng, Z., Yu, Z.L., Wu, Q., Wang, Y.H., Zhao, T.C.,* Xie, Y.F.,*. Metal-polyphenol Multistage Competitive Coordination System for Colorimetric Monitoring Meat Freshness. Advanced Materials, 2025, 37, 2503246. (IF=27.4，封面文章)

[2]Jin, Y., Hu, Z.Y., Xu, H.W., Cheng, J., Yu, Z. L., Yao, W. R., Zhao, T.C., Ji, W., * Yukihiro Ozaki.,* Xie, Y.F.,*. Bioinspired Turing-Nanoarchitected Needle for Solid Matrices Analysis: A Universal Platform Enabling Dual-Scale SERS Enhancement. Advanced Materials, 2025, 2506426. (IF=27.4)

[3]Xu,H.W., Yu,Z.L., Dong, C.L., Yao, W.R., Xie, Y.F.,*. Cap opening induced microplastic contamination in bottled water revealed by single particle FTIR imaging and analysis, Food Control, 2025, 178, 111508.(IF=5.6)

[4]Xu, H.W., Dong, C.L., Zhang, B., Jin, Y., Cheng, J., Yu, Z.L.,Yukihiro Ozaki., Yu, J.I., Ma, D., Xie, Y.F.,*. The role of microplastics in elevated risk and tissues metabolic alterations in uterine fibroid of female patients. Environmental Pollution. 2025, 374, 126251(IF=7.6)

[5]Zhao, J. J., Sun, L., Dong, Y, M., Chang, Y. X., Wang, H. S., Liu, Z. H., Li, J. B., Xie, Y.F.,*, Ji, W.,*. Semiconductor Superstructures with Multiple Synergistic Resonances for SERS Exploring Multiplex Noncovalent Interactions. Nano Letters.2025, 25, 6645-6653.(IF=9.6)

[6]Cheng, J., Zhuang, S.Q., Luo, Z.W., Chen, S.T., Shen, Y., Ye, J., Yu, Z.L., Zhao, T.C.,* Xie, Y.F., *. Simple and rapid capillarity-assisted ultra-trace detection of thiram on apple surface with a silver nanoparticles/fflter paper SERS substrate. Journal of Hazardous Materials, 2025, 485, 136945.(IF=12.2)

[7]Xu, H.W., Dong, C.L., Xiang, T.Y., Shentu, X.Z., Yu, Z.L., Xu, J., Yu, J.J., Ma, D.,* Xie, Y.F.,*. Microplastic changes during the development of cervical cancer and its effects on the metabolomic profiles of cancer tissues. Journal of Hazardous Materials, 2025, 483, 136656.(IF=12.2)

[8]Xu, C., Li, J.B., Liu, J., Ma, Y.X., Wang, X.S., Xie, Y, F.,* Chen, C.X., Ji, W.,*. Rapid construction of interfacial plasmonic nanoarray for SERS sensing of flavonoids. Biosensors and Bioelectronics, 2025, 271, 117044.(IF=10.7)

[9]Zhao, Y, L., Dina M. El-Sherif, Cheng, J., Zhang, H., Hu, Z, Y., Wu, Q., Shen, H., Yu, Z, L.,* , Xie, Y, F.,*. Carboxymethyl cellulose-based colorimetric sensor array incorporating ionic liquid-tuned anthocyanin and nano-silica coating for pork freshness monitoring. Food Hydrocolloids, 2025, 158, 110601.(IF=11.0)

[10]Hu, Z.Y., Xiang, T.Y., Jin, Y., Sun, Y.Y., Huang, L.J., Yu, Z.L., Xie, Y, F.,*. Ultrasonic-enhanced plasma-activated microbubble water for pre-inactivation of pathogenic microorganisms and activated mist alleviates quality deterioration of fresh-cut romaine lettuce. Food Bioscience, 2024, 62, 105481.(IF=4.8)

[11]Hu, Z, Y., Xu, H, W., Cheng, J., Zhang, H., Zhao, Y, L., Hu, J., Sun, Y, Y., Huang, L, J., Yao, W, R., Yu, Z, L., Xie, Y, F.,*. Catalyst-free regeneration of plasma-activated water via ultrasonic cavitation: Removing aggregation concealment of antibiotic-resistant bacteria with enhanced wastewater sustainability. Journal of Hazardous Materials, 2024, 479, 135705.(IF=12.2)

[12]Lu, J, H., Qin, H, C., Liang, L, L., Fang, J, Q., Hao, K, W., Song, Y, X., Sun, T, X., Hui, G.,* Xie, Y, F.,* Zhao,Y.,*. Yam protein ameliorates cyclophosphamide-induced intestinal immunosuppression by regulating gut microbiota and its metabolites. International Journal of Biological Macromolecules, 2024, 279, 135415.(IF=7.7)

[13]Xu, H, W., Dong, C, L., Yu, Z, L., Hu, Z, Y., Yu, J, J., Ma, D., Yao, W, R., Qi, X, W., Yukihiro, Ozaki.,* Xie, Y, F.,*. First identification of microplastics in human uterine fibroids and myometrium. Environmental Pollution, 2024, 360, 124632.(IF=7.6)

[14]Xu, H, W., Dong, C, L., Yu, Z, L., Yukihiro, Ozaki., Hu, Z, Y., Zhang, B., Yao, W, R., Yu, J, J.,* Xie, Y, F.,*. Detection and analysis of microplastics in tissues and blood of human cervical cancer patients. Environmental Research, 2024, 259, 119498.(IF=7.7)

[15]Xiang, T.Y., Sun, Y.Y., Ding, D.Z., Yao, W.R., Yu, Z.L., & Xie, Y. F.,*. Microscopic Raman-based rapid detection of submicron/nano polypropylene plastics in tea and tea beverages. Food chemistry, 2024,454, 139657.(IF=8.5)

[16]Yang, Y., Li, Y.F., Xie, Q.H., Jiang, B., Li, J.B., Xie, Y. F.,* Ji, W.,*. Evaluating the Kinetics and Molecular Mechanism for Biomimetic Metabolic Activation of PAHs by Surface-Enhanced Raman Scattering Spectroscopy. Analytical Chemistry, 2024, 96, 25, 10365-10372.(IF=6.8)

[17]Li, J. F., Xie, Q. H., Li. J. B., Sun, L., Xie, Y.F.,* Yukihiro Ozaki,* Ji, W.,*. Macroscale TiO₂Microspherical Arrays with Multiple Synergistic Effect for Highly Sensitive Surface-Enhanced Raman Scattering. Advanced Functional Materials, 2024, 2400523.(IF=18.5)

[18]Hu, Z. Y., Xu, W. Z., Sun, Y. Y., Xu, H. W., Xu, J., Huang, L. J., Yao, W. R., Yu, Z. L.,* Xie, Y. F.,*. Ultrasound-assisted activation of PAW residual radicals in the concurrent elimination of ARB and ARGs: Process efficiency, mechanism and implication. Chemical Engineering Journal, 2024, 482, 148627.(IF=13.3)

[19]Liu, Q.R., Chen, Z., Chen, Y.L., Yang, F.W., Yao, W.R., & Xie, Y.F.,*. Microplastics contamination in eggs: Detection, occurrence and status. Food Chemistry, 2022, 397, 133771.(IF=8.5)

[20]Yang, F.W., Mi, J.Q., Huang, F., Pienpinijtham, P., Guo, Y.H., Cheng, Y.L., Yao, W.R., & Xie, Y.F.,*. Trans-cinnamaldehyde inhibits Penicillium italicum by damaging mitochondria and inducing apoptosis mechanisms. Food Science and Human Wellness, 2022, 11,975-981.(IF=5.6)

奖励

1.2023年度中国商业联合会技术发明奖，特等奖（1/9），食品中典型化学危害物光谱快检关键技术及应用

2.2021年度中国轻工业联合会技术发明奖，三等奖（1/6），食品污染物快速识别与检测关键技术

3.2018年度中国轻工业联合会技术发明奖，三等奖（1/6），食品安全快速检测技术和应用

4.2016年度全国商业科技进步奖，一等奖（2/8），基于表面增强拉曼技术的食品安全快速检测的应用

5.2016年度中国轻工联合会科学技术发明奖，二等奖（2/6），基于表面增强拉曼技术食品安全快速检测的应用

授权专利：

1.国际专利（巴黎公约）：拉曼光谱表征反复冻融过程中牛肉脂肪品质变化的方法（US10126245）.谢云飞，陈清敏，姚卫蓉，郭亚辉，成玉梁，钱和. Method for representing quality change process of beef fat during repeated freezing and thawing through Raman spectrum.

2.日本专利：一种等离子体活化水协同酒石酸处理鲜切果蔬保鲜的方法（特许第7662842号）谢云飞，张静.アラズマ活性化水と酒石酸を併用してカット果菜を処理する鮮度保持方法.

3.抗菌药呋喃唑酮和呋喃西林的表面增强拉曼光谱检测方法(ZL201210417752.9).谢云飞，竺芯宇，吉薇，郇楠，陈婷，姚卫蓉，汪何雅，钱和

4.一种利用光照和表面增强拉曼快速检测氟虫腈的方法(ZL2018103157120).谢云飞，许乐贝，姚卫蓉，于航，郭亚辉，成玉梁

5.一种基于拉曼光谱技术的鸡蛋新鲜度无损检测方法(ZL202010023268.2).谢云飞，刘宇良，姚卫蓉，于航，郭亚辉，成玉梁，张颖，张亦驰

6.一种定量评价鸡蛋胶护膜品质的方法(ZL202011017363.8).谢云飞，解舟

7.一种猪肉中齐帕特罗残留的快速检测方法(ZL202011555659.5).谢云飞，董祥辉，施思倩，姚卫蓉，孙莹莹，邱险辉

8.一种基于表面增强拉曼光谱检测氟尼辛葡甲胺残留的方法（CN2020116100819）.谢云飞，张茜，董祥辉，姚卫蓉，于航，成玉梁，郭亚辉.

9.一种细菌群体感应抑制剂及其应用（ZL 202110109905.2）.谢云飞，刘宇，姚卫蓉，于航，杨方威，郭亚辉.

10.一种某于Au@ZIF-8基底检测双酚A残留的方法（ZL 202210306297.9）.谢云飞，董祥辉，姚卫蓉